What is Exposome?

Recently the word exposome has been making frequent appearances. The term exposome was first introduced in 2005 by Christopher Paul Wild, a cancer epidemiologist, and has since branched out and has made its way into the cosmetic and skin care industry more frequently and predominantly.

Exposome has been defined as the totality of human exposure to the environment from  conception up until death. This includes both external and internal factors as well as the human body’s response to these factors.

Most of the factors and the responses of the body to these factors has led to clinical and biological signs of skin ageing.

Exposome factors that affect skin ageing include but are not limited to:

  • Solar radiation
  • Air pollution
  • Tobacco smoking
  • Nutrition
  • Stress
  • Sleep deprivation
  • Temperature
  • Cosmetics

The above exposome factors have been identified to increase the effect overall skin ageing and how it is different and unique to each individual.

It is without doubt that significant progress has been made in understanding the underlying molecular and cellular mechanisms of the body and how it all comes together to affect visible signs of ageing.

A better understanding of the interaction of distinct exposomal factors with each other and the resulting effects as it concerns skin ageing is key to optimising existing and enable the development of better anti-skin ageing strategies and products.

Overall, exposome refers to the total exposure of factors that the body is exposed to both internally and externally during its lifetime.

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